Periodontitis and systemic diseases
According to the latest scientific evidence, periodontitis is a risk factor for the onset and development of major systemic diseases. The high concentration of pathogenic bacteria in periodontal lesions causes episodes of bacteremia and the placing in the circulation of toxins, connectable at the beginning and progression of major systemic diseases: respiratory diseases, cardiovascular diseases, bacterial contamination of the valve and of the atheromatous plaques. It also demonstrated the existence of a two-way link with diabetes mellitus (strong predisposition of diabetic periodontitis, increased difficulty of glucose metabolic control if it is not treated). Even the placental filter can be by passed with a consequent increase of the mediators responsible for the premature birth and the possibility of low birth weight.
Epidemiological studies suggest that more than 15% of the population of the Western countries suffers from serious forms of periodontal disease and emerging evidence demonstrates a clear relationship between the effects of chronic oral inflammation and general health. The link between systemic diseases and periodontitis is forged by the inflammatory mechanisms involved and is so strong that periodontal disease is considered a risk factor for development of systemic diseases and, conversely, that certain systemic diseases can have a significant impact on oral health.
Upwards of 100 systemic disorders manifest with oral symptoms; for example, cardiovascular diseases, stroke, respiratory-tract infections, pancreatic cancer, diabetes, and nutritional problems.
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