Tests utility

  • Test efficacy

Efficacy of the Periodontal Bacterial Assessment (BPA)

The Biomolecular Diagnostic research laboratories have been set up for the purpose of providing a highly specialised analysis service in the dental sector. The Bacterial Periodontal Assessment is the result of a validated and standardised protocol on thousands of tests, and it represents an indispensable product for the dental clinic. The identification and quantification of the main periodontal pathogens assists and guides the clinician during the phase of diagnosing the disease, and allows for drawing up a personalised and biologically-guided periodontal treatment plan.

Biomolecular Diagnostic also represents an objective monitoring instrument of the therapeutic intervention and the maintenance protocol. Retrospective studies conducted by our researchers have demonstrated that there is a statistically significant correspondence between the results of the microbiological analyses and the clinical picture. Moreover, the post-therapy restoring of a microbiological structure that can be associated with a state of good periodontal health, corresponds to an improvement in the clinical parameters in terms of bone regeneration, a reduction in the depth of the pocket, and the absence of bleeding and suppuration.

Effectiveness of the Genetic Periodontal Screening (GPS) test

The Biomolecular Diagnostic researchers have been pioneers in creating the only test in the world that can assess the risk of periodontitis (Genetic Periodontal Screening), thereby allowing the clinician to personalise the therapeutic plan based on the gene structure relating to the main molecules involved in the regulation of the inflammatory process and bone metabolism.

Genetic Periodontal Screening also represents a valid screening tool for use in subjects not suffering from periodontitis in order to assess their susceptibility to developing periodontitis.
The combined use of the GPS test and the BPA test constitutes an innovative and indispensable instrument ensuring a personalised and biologically-guided approach to periodontal treatment.

Effectiveness of Assessment Test of enzyme MMP-8

The evaluation of the enzyme activity of MMP-8 in crevicular or sulcus fluid is an additional tool available to support the specialist during the diagnosis process and in the course of periodontal/peri-implant therapy. The test is able to detection the inflammation of tissues of the oral cavity during early signs of gingivitis and mucositis, allowing the specialist to take preventive treatments that avoid more invasive interventions or failure of implant surgery. Scientific research also shows that increased levels of aMMP-8 correlates with the active phase and progression of periodontal and peri-implant disease resulting in worsening clinical parameters, tissue damage leading to the loss of teeth and/or implant. The reduction or disappearance of enzyme activity of MMP-8 evaluated with after-treatment tests, reveals the therapeutic efficacy and establishes the restoration of health conditions at periodontal and peri-implant level.

PerioSafe Pro: easy and fast testing before each session at the dentist

All dentists can use PerioSafe Pro before each session to detect high levels of AMMP-8 in the oral cavity of patients. PerioSafe detects early degenerative processes of periodontal tissue and is therefore useful to prevent periodontitis.

For those patients for whom periodontitis may represent a risk, such as diabetics, heart patients, patients afflicted with rheumatoid arthritis, women who wish to have a child, the early identification of a potential risk of periodontal disease is very important.

Monitoring as support in periodontal treatment

The diagnostic test for the risk of periodontal disease is recommended to all patients and any inspection before the professional cleaning, so once or twice a year.

Early and professional intervention can prevent the arise of periodontal disease: this test identifies the risk of developing the disease before any traditional method, like sampling and X-rays control, reveal an ongoing degeneration of the tissue. In order to reliably identify the collagenolytic deterioration of the tissue that occurs in waves (6-12 months increments), AMMP-8 screening must be made at least once a year as part of regular check-ups as prevention and observance of a periodontal therapy.Thanks to PerioSafe this is now a quick and easy process.